2-furoate—CoA ligase

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2-furoate-CoA ligase
Identifiers
EC number 6.2.1.31
CAS number Template:CAS
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a 2-furoate—CoA ligase (EC 6.2.1.31) is an enzyme that catalyzes the chemical reaction

ATP + 2-furoate + CoA \rightleftharpoons AMP + diphosphate + 2-furoyl-CoA

The 3 substrates of this enzyme are ATP, 2-furoate, and CoA, whereas its 3 products are AMP, diphosphate, and 2-furoyl-CoA.

This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is 2-furoate:CoA ligase (AMP-forming). This enzyme is also called 2-furoyl coenzyme A synthetase.

References

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