D-alanine—D-serine ligase

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D-alanine—D-serine ligase
Identifiers
EC number 6.3.2.35
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

D-alanine—D-serine ligase (EC 6.3.2.35, VanC, VanE, VanG) is an enzyme with systematic name D-alanine:D-serine ligase (ADP-forming).[1][2][3][4][5] This enzyme catalyses the following chemical reaction

D-alanine + D-serine + ATP \rightleftharpoons D-alanyl-D-serine + ADP + phosphate

The product of this enzyme, D-alanyl-D-serine, can be incorporated into the peptidoglycan pentapeptide instead of the usual D-alanyl-D-alanine dipeptide.

References

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External links

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