Inositol-hexakisphosphate kinase

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Inositol-hexakisphosphate kinase
Identifiers
EC number 2.7.4.21
CAS number Template:CAS
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Inositol-hexakisphosphate kinase (EC 2.7.4.21, ATP:1D-myo-inositol-hexakisphosphate phosphotransferase) is an enzyme with systematic name ATP:1D-myo-inositol-hexakisphosphate 5-phosphotransferase.[1][2][3] This enzyme catalyses the following chemical reaction

(1) ATP + 1D-myo-inositol hexakisphosphate \rightleftharpoons ADP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate
(2) ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate \rightleftharpoons ADP + 1D-myo-inositol diphosphate tetrakisphosphate (isomeric configuration unknown)

Three mammalian isoforms are known to exist.

See also

References

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External links

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