Insulysin

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Insulysin
Identifiers
EC number 3.4.24.56
CAS number Template:CAS
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Insulysin (EC 3.4.24.56, insulinase, insulin-degrading enzyme, insulin protease, insulin proteinase, insulin-degrading neutral proteinase, insulin-specific protease, insulin-glucagon protease, metalloinsulinase, IDE) is an enzyme.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

Degradation of insulin, glucagon and other polypeptides. No action on proteins

This cytosolic enzyme is present in mammals and the fruit fly, Drosophila melanogaster.

References

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http://www.jneurosci.org/content/20/23/8745.full

See also

External links

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