Dimethylallyltranstransferase

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Lua error in Module:Infobox at line 235: malformed pattern (missing ']'). Lua error in Module:Infobox at line 235: malformed pattern (missing ']'). Dimethylallyltranstransferase is an enzyme that converts dimethylallylpyrophosphate and isopentenyl pyrophosphate into farnesylpyrophosphate.^[1]^[2] It is also referred to as farnesylpyrophosphate synthase or farnesyldiphosphate synthase.

Pyrophosphate is also involved, as both a reactant and a product. Geranylpyrophosphate is created in an intermediate step.

References

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See also

Geranyltranstransferase

External links

Dimethylallyltranstransferase at the US National Library of Medicine Medical Subject Headings (MeSH)

Metabolism: lipid metabolism – ketones/cholesterol synthesis enzymes/steroid metabolism

Mevalonate pathway

To HMG-CoA	Acetyl-Coenzyme A acetyltransferase HMG-CoA synthase (regulated step)
Ketogenesis	HMG-CoA lyase 3-hydroxybutyrate dehydrogenase Thiophorase
To Mevalonic acid	HMG-CoA reductase
To DMAPP	Mevalonate kinase Phosphomevalonate kinase Pyrophosphomevalonate decarboxylase Isopentenyl-diphosphate delta isomerase
Geranyl-	Dimethylallyltranstransferase Geranyl pyrophosphate

To lanosterol	Farnesyl-diphosphate farnesyltransferase Squalene monooxygenase Lanosterol synthase
7-Dehydrocholesterol path	Lanosterol 14α-demethylase Sterol-C5-desaturase-like 7-Dehydrocholesterol reductase
Desmosterol path	24-dehydrocholesterol reductase

Steroidogenesis

To pregnenolone

Side-chain cleavage

To corticosteroids

aldosterone: 18-hydroxylase

To sex hormones

To androgens	17α-hydroxylase/17,20 lyase 3β dehydrogenase 17β dehydrogenase 5α reductase 1 2
To estrogens	Aromatase

Other/ungrouped

Steroid metabolism: sulfatase
- Steroid sulfatase
sulfotransferase
- SULT1A1
- SULT2A1

v t e Transferases: alkyl and aryl (EC 2.5)
2.5.1	Dimethylallyltranstransferase Thiaminase I Methionine adenosyltransferase Riboflavin synthase Dihydropteroate synthase Spermidine synthase Glutathione S-transferase Farnesyl-diphosphate farnesyltransferase Spermine synthase Alkylglycerone phosphate synthase Farnesyltransferase Geranylgeranyltransferase type 1 Porphobilinogen deaminase

Proteins: enzymes

Activity

Regulation

Classification

Types

EC1 Oxidoreductases(list)
EC2 Transferases(list)
EC3 Hydrolases(list)
EC4 Lyases(list)
EC5 Isomerases(list)
EC6 Ligases(list)

Molecular and Cellular Biology portal

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