ABCA2
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). ATP-binding cassette sub-family A member 2 is a protein that in humans is encoded by the ABCA2 gene.[1][2]
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene.[2]
See also
References
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External links
- ABCA2 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
- ABCA2 human gene location in the UCSC Genome Browser.
- ABCA2 human gene details in the UCSC Genome Browser.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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