AC927
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| File:AC927.png | |
| Systematic (IUPAC) name | |
|---|---|
|
1-(2-phenylethyl)piperidine
|
|
| Identifiers | |
| CAS Number | 332-14-9 |
| ChemSpider | 9141 |
| Chemical data | |
| Formula | C13H19N |
| Molecular mass | 189.30 g/mol |
AC927 or 1-(2-phenylethyl)piperidine is a selective sigma receptor antagonist, with reported binding affinity of Ki = 30 ± 2 nM for the sigma-1 receptor and Ki = 138 ± 18 nM for the sigma-2 receptor, and negligible binding affinity for other major central nervous system receptors, transporters, and ion channels.[1]
AC927 is reported to attenuate the locomotor stimulation induced by methamphetamine in mice.[1]
References
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- Piperidines
