ARHGEF12
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Rho guanine nucleotide exchange factor 12 is a protein that in humans is encoded by the ARHGEF12 gene.[1][2][3]
Function
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptor . The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals.[3]
Clinical significance
This protein is observed to form myeloid/lymphoid fusion partner in acute myeloid leukemia.[3]
Interactions
ARHGEF12 has been shown to interact with:
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References
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<references />, or <references group="..." />Further reading
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This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it. |
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