Asunaprevir
From Infogalactic: the planetary knowledge core
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Names | |
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IUPAC name
3-Methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl-(4R)-4-[(7-chloro-4-methoxy-1-isoquinolinyl)oxy]-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-vinylcyclopropyl}-L-prolinamide
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Other names
BMS-650032
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Identifiers | |
630420-16-5 | |
ChEMBL | ChEMBL2105735 |
ChemSpider | 17235944 |
Jmol 3D model | Interactive image |
KEGG | D10093 |
PubChem | 16076883 |
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Properties | |
C35H46ClN5O9S | |
Molar mass | 748.29 g·mol−1 |
Pharmacology | |
ATC code | J05 |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
Asunaprevir (formerly BMS-650032, brand name in Japan and Russia[1] Sunvepra) is an experimental drug candidate for the treatment of hepatitis C. It is undergoing development by Bristol-Myers Squibb and is currently in Phase III clinical trials.[2]
Asunaprevir is an inhibitor of the hepatitis C virus enzyme serine protease NS3.[3]
Asunaprevir is being tested in combination with pegylated interferon and ribavirin, as well as in interferon-free regimens with other direct-acting antiviral agents including daclatasvir.[4][5][6]
See also
References
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- ↑ AASLD: Daclatasvir plus Asunaprevir Rapidly Suppresses HCV in Prior Null Responders. Highleyman, L. HIVandHepatitis.com. 8 November 2011.
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- Articles containing unverified chemical infoboxes
- NS3/4A protease inhibitor
- Cyclopropanes
- Carbamates
- Isoquinolines
- Sulfonamides
- Chloroarenes
- Pyrrolidines
- Antiinfective agent stubs