Meprodine

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Alpha-meprodine
Alphameprodine.svg
Systematic (IUPAC) name
(3S,4R)-3-ethyl-1-methyl-4-phenylpiperidin-4-yl propionate
Clinical data
Legal status
Identifiers
CAS Number 468-51-9
ATC code none
PubChem CID: 61119
ChemSpider 16736823 YesY
ChEMBL CHEMBL2104027
Chemical data
Formula C17H25NO2
Molecular mass 275.39 g/mol
  • CC[C@H]1CN(C)CC[C@@]1(OC(=O)CC)c2ccccc2
  • InChI=1S/C17H25NO2/c1-4-14-13-18(3)12-11-17(14,20-16(19)5-2)15-9-7-6-8-10-15/h6-10,14H,4-5,11-13H2,1-3H3/t14-,17-/m0/s1 YesY
  • Key:ODEGQXRCQDVXSJ-YOEHRIQHSA-N YesY
  (verify)

Meprodine is an opioid analgesic that is an analogue of pethidine (meperidine). It is closely related to the drug prodine, the only difference being that meprodine has an ethyl group rather than a methyl at the 3-position of the piperidine ring.

As with prodine, there are two isomers of meprodine, alpha-meprodine and beta-meprodine, with the alpha isomer having been more widely used.

Meprodine has similar effects to other opioids, and produces analgesia, sedation and euphoria. Side effects can include itching, nausea and potentially serious respiratory depression which can be life-threatening.

References



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