CD244

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). CD244 (Cluster of Differentiation 244) is a human protein encoded by the CD244 gene.[1] It is also known as Natural Killer Cell Receptor 2B4[2]

This gene encodes a cell surface receptor expressed on natural killer cells (NK cells) (and some T cells) mediating non-major histocompatibility complex (MHC) restricted killing. The interaction between NK-cell and target cells via this receptor is thought to modulate NK-cell cytolytic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[3] CD244 can also be expressed on non-lymphocytes such as eosinophils, mast cells and dendritic cells.[4]


See also

References

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Further reading

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External links


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  1. Lua error in package.lua at line 80: module 'strict' not found.
  2. Online 'Mendelian Inheritance in Man' (OMIM) 605554
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