Clofoctol

Clofoctol

Structural formula of clofoctol
Ball-and-stick model of the clofoctol molecule
Systematic (IUPAC) name
2-[(2,4-dichlorophenyl)methyl]- 4-(2,4,4-trimethylpentan-2-yl)phenol
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of administration	Rectal (suppository)
Pharmacokinetic data
Bioavailability	98%
Metabolism	Hepatic glucuronidation
Excretion	Biliary
Identifiers
CAS Number	37693-01-9 Y
ATC code	J01XX03 (WHO)
PubChem	CID: 2799
ChemSpider	2697 Y
UNII	704083NI0R Y
KEGG	D07244 Y
ChEMBL	CHEMBL1476605
Chemical data
Formula	C21H26Cl2O
Molecular mass	365.336 g/mol
SMILES Clc1cc(Cl)ccc1Cc2cc(ccc2O)C(C)(C)CC(C)(C)C
InChI InChI=1S/C21H26Cl2O/c1-20(2,3)13-21(4,5)16-7-9-19(24)15(11-16)10-14-6-8-17(22)12-18(14)23/h6-9,11-12,24H,10,13H2,1-5H3 Y Key:HQVZOORKDNCGCK-UHFFFAOYSA-N Y
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Clofoctol is a bacteriostatic antibiotic. It is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. It is marketed in France under the trade name Octoplus and in Italy as Gramplus.

It is only functional against Gram-positive bacteria.

It penetrates into human lung tissue.