Fludroxycortide

Fludroxycortide

Systematic (IUPAC) name
6-Fluoro-11,21-dihydroxy-16,17-[(l-methylethylidene)bis(oxy)]-(6α,11β,16α)-pregn-4-ene-3,20-dione
Clinical data
Trade names	Cordran, Haelan
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Legal status	UK: POM (Prescription only)
Routes of administration	Topical
Identifiers
CAS Number	1524-88-5 Y
ATC code	D07AC07 (WHO)
PubChem	CID: 15209
IUPHAR/BPS	7606
DrugBank	DB00846 Y
ChemSpider	14475 Y
UNII	8EUL29XUQT Y
KEGG	D00328 Y
ChEMBL	CHEMBL1201012 N
Chemical data
Formula	C24H33FO6
Molecular mass	436.514 g/mol
SMILES O=C1\C=C5/[C@](C)(CC1)[C@@H]2[C@H]([C@H]3[C@](C[C@@H]2O)([C@@]4(OC(O[C@@H]4C3)(C)C)C(=O)CO)C)C[C@@H]5F
InChI InChI=1S/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1 Y Key:POPFMWWJOGLOIF-XWCQMRHXSA-N Y
NY (what is this?)  (verify)

Fludroxycortide (INN, also known as flurandrenolone or flurandrenolide) is a synthetic topical steroid and is used as an anti-inflammatory treatment for use on skin irritations. Trade names include Haelan (Typharm, UK) and Cordran (by Watson Pharmaceuticals, US).

Fludroxycortide is available in ointment, cream and as an impregnated tape (Haelan tape, Cordran tape). Licensed indications in the United Kingdom include recalcitrant dermatoses.