GLRA3

Glycine receptor, alpha 3
Identifiers
Symbol	GLRA3
External IDs	OMIM: 600421 MGI: 95749 HomoloGene: 142 IUPHAR: 425 ChEMBL: 1075092 GeneCards: GLRA3 Gene
Gene ontology Molecular function • glycine binding • extracellular-glycine-gated chloride channel activity • transmitter-gated ion channel activity Cellular component • plasma membrane • integral component of plasma membrane • external side of plasma membrane • cell junction • chloride channel complex • neuron projection • axon terminus • synapse • postsynaptic membrane Biological process • neuropeptide signaling pathway • ion transmembrane transport • regulation of membrane potential • response to amino acid • neurological system process • transmembrane transport • synaptic transmission, glycinergic • gamma-aminobutyric acid receptor clustering • chloride transmembrane transport Sources: Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	8001	110304
Ensembl	ENSG00000145451	ENSMUSG00000038257
UniProt	O75311	Q91XP5
RefSeq (mRNA)	NM_001042543	NM_080438
RefSeq (protein)	NP_001036008	NP_536686
Location (UCSC)	Chr 4: 174.64 – 174.83 Mb	Chr 8: 55.94 – 56.13 Mb
PubMed search	[1]	[2]

The Glycine receptor subunit alpha-3 is a protein that in humans is encoded by the GLRA3 gene. The protein encoded by this gene is a subunit of the glycine receptor.

Variants of this receptor subunit is associated with susceptibility to epilepsy.

External links

• GLRA3 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)