GlobeImmune
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| Public | |
| Traded as | NASDAQ: GBIM |
| Industry | Biotechnology |
| Headquarters | Louisville, Colorado, United States |
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Number of employees
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22 (Dec 2014)[1] |
| Website | GlobeImmune.com |
GlobeImmune, Inc. is a clinical-stage public biopharmaceutical company headquartered in Louisville, Colorado, that develops therapeutic vaccines to treat cancer and infectious diseases.[2] As of August 2014[update], the company had no marketed products.[3] GlobeImmune’s therapeutic vaccines are developed on the company’s Tarmogen immunotherapy platform. Tarmogens are made from genetically modified yeast that express one or more disease-associated antigens. Tarmogens activate T cells to specifically target and eliminate diseased cells with the same target antigen.
The company has partnerships with Celgene (established in 2009)[2] and the National Cancer Institute for the development of cancer vaccines,[4][5] and with Gilead for the development of therapeutic vaccines for the treatment of hepatitis B.[6]
With respect to financing in the absence of revenue, the company raised US$17.5 million through a Series E Preferred Stock offering in January 2010.[2]
As of August 2015[update], GlobeImmune had two therapeutic vaccines in clinical trials, GI-6207 and GI-6301, for the treatment of various cancers.[7] Completed trials have addressed two other candidates, GI-4000 (the company's lead oncology candidate as of 2010)[2] and GI-5005.[7] Despite there being three ongoing trials, in July 2015 the company announced it would eliminate "most of its workforce positions" shortly following the failure of a trial examining GI-4774.[1]
References
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