HEAT repeat domain

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The HEAT repeat domain is a solenoid protein domain found in a number of cytoplasmic proteins including the four that the give rise to the acronym HEAT (Huntingtin, elongation factor 3 (EF3), protein phosphatase 2A (PP2A), and the yeast kinase TOR1).[2] HEAT repeats form rod-like helical structures which are involved in intracellular transport; they are structurally related to armadillo repeats. The nuclear transport protein importin beta contains 19 HEAT repeats.

References

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