Ifetroban

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Ifetroban
Ifetroban structure.png
Systematic (IUPAC) name
3-[2-({(1S,2R,3S)-3-[4-(pentylcarbamoyl)-1,3-oxazol-2-yl]-7-oxabicyclo[2.2.1]hept-2-yl}methyl)phenyl]propanoic acid
Identifiers
CAS Number 143443-90-7
PubChem CID: 23724921
ChemSpider 58452
UNII E833KT807K YesY
KEGG D04500
ChEMBL CHEMBL2146062
Chemical data
Formula C25H32N2O5
Molecular mass 440.53 g/mol
  • O=C(NCCCCC)c1nc(oc1)[C@@H]4C2O[C@@H](CC2)[C@@H]4Cc3ccccc3CCC(=O)O

Ifetroban is a potent and selective thromboxane receptor antagonist.[1]

Synthesis

Ifetroban synthesis: Drugs Future (c.f. Lednicer book 6).

References

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