Inositol-pentakisphosphate 2-kinase

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Inositol-pentakisphosphate 2-kinase
Identifiers
EC number 2.7.1.158
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

In enzymology, an inositol-pentakisphosphate 2-kinase (EC 2.7.1.158) is an enzyme that catalyzes the chemical reaction

ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate \rightleftharpoons ADP + 1D-myo-inositol hexakisphosphate

Thus, the two substrates of this enzyme are ATP and 1D-myo-inositol 1,3,4,5,6-pentakisphosphate, whereas its two products are ADP and 1D-myo-inositol hexakisphosphate.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is ATP:1D-myo-inositol 1,3,4,5,6-pentakisphosphate 2-phosphotransferase. Other names in common use include IP5 2-kinase, Gsl1p, Ipk1p, inositol polyphosphate kinase, inositol 1,3,4,5,6-pentakisphosphate 2-kinase, and Ins(1,3,4,5,6)P5 2-kinase.

References

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