Interstitial collagenase
From Infogalactic: the planetary knowledge core
| Interstitial collagenase | |||||||||
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| 270px
collagenase monomer, Human fibroblast
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| Identifiers | |||||||||
| EC number | 3.4.24.7 | ||||||||
| CAS number | Template:CAS | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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Interstitial collagenase (EC 3.4.24.7, vertebrate collagenase, matrix metalloproteinase 1) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction
- Cleavage of the triple helix of collagen at about three-quarters of the length of the molecule from the N-terminus, at Gly775-Ile in the alpha1(I) chain. Cleaves synthetic substrates and alpha-macroglobulins at bonds where P1' is a hydrophobic residue
This enzyme belongs to the peptidase family M10.
See also
References
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<references />, or <references group="..." />External links
- Interstitial collagenase at the US National Library of Medicine Medical Subject Headings (MeSH)
