Iodobenzamide

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Iodobenzamide
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Names
IUPAC name
N-{[(2S)-1-Ethylpyrrolidin-2-yl]methyl}-2-hydroxy-3-iodo-6-methoxybenzamide
Other names
IBZM; Iolopride
Identifiers
84226-06-2 YesY
113716-48-6 (123I) YesY
113452-80-5 (125I) YesY
ChemSpider 123I).html 97107(123I)
Jmol 3D model Interactive image
PubChem 107995
  • InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1
    Key: CANPFCFJURGKAX-JTQLQIEISA-N
  • InChI=1/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1
    Key: CANPFCFJURGKAX-JTQLQIEIBE
  • Ic1ccc(OC)c(c1O)C(=O)NC[C@H]2N(CC)CCC2
Properties
C15H21IN2O3
Molar mass 404.25 g·mol−1
Pharmacology
ATC code V09AB02
Vapor pressure {{{value}}}
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

IBZM (abbreviation for iodobenzamide) is a chemical substance. Pharmaceutically it is a dopamine antagonist and it can be used by nuclear medicine physicians as a radioactive tracer for SPECT where the radioactive isotope is iodine-123 or iodine-125.[1][2] The main purpose of a brain study with IBZM is the differentiation of Parkinson's disease from other neurodegenerative diseases such as Lewy Body dementia and multiple system atrophy.

References

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