Loganate O-methyltransferase

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loganate O-methyltransferase
Identifiers
EC number 2.1.1.50
CAS number Template:CAS
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a loganate O-methyltransferase (EC 2.1.1.50) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + loganic acid \rightleftharpoons S-adenosyl-L-homocysteine + loganin

Thus, the two substrates of this enzyme are S-adenosyl methionine and loganic acid (also called loganate), whereas its two products are S-adenosylhomocysteine and loganin.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:loganate 11-O-methyltransferase. Other names in common use include loganate methyltransferase, and S-adenosyl-L-methionine:loganic acid methyltransferase. This enzyme participates in terpene indole and ipecac alkaloid biosynthesis.

References

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