Ornidazole

Ornidazole
Systematic (IUPAC) name
	1-Chloro-3-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ol
Clinical data
Trade names	Xynor
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
Pharmacokinetic data
Metabolism	Metabolized via the liver, excreted in the Urine and Feces
Excretion	85% of single oral dose is eliminated with 5 days - Urine (63%) and Feces (22%)
Identifiers
CAS Number	16773-42-5
ATC code	G01AF06 (WHO) J01XD03 P01AB03 QP51AA03 (WHO)
PubChem	CID: 28061
ChemSpider	26102
UNII	62XCK0G93T
KEGG	D05274
ChEBI	CHEBI:75176
ChEMBL	CHEMBL1449676
Chemical data
Formula	C7H10ClN3O3
Molecular mass	219.625 g/mol
	SMILES [O-][N+](=O)c1cnc(n1CC(O)CCl)C ;
	InChI InChI=1S/C7H10ClN3O3/c1-5-9-3-7(11(13)14)10(5)4-6(12)2-8/h3,6,12H,2,4H2,1H3 ; Key:IPWKIXLWTCNBKN-UHFFFAOYSA-N ;
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Ornidazole is a drug that cures some protozoan infections. It has been investigated for use in Crohn's disease after bowel resection.^[1]

Synthesis is a straightforward reaction between 2-methyl-nitroimidazole and epichlorohydrin under acid catalyst conditions.^[2]

References

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