TIMP3

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Metalloproteinase inhibitor 3 is an protein that in humans is encoded by the TIMP3 gene.[1][2]

This gene belongs to the tissue inhibitor of metalloproteinases gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.[3]

See also

References

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Further reading

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External links

  • The MEROPS online database for peptidases and their inhibitors: I35.003



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  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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