TRA@

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T cell receptor alpha locus

Identifiers

TRA ; IMD7; TCRA; TCRD; TRA@; TRAC

External IDs

OMIM: 186880 GeneCards: TRA Gene

Gene ontology
Molecular function	• receptor activity • protein binding • MHC protein binding • peptide antigen binding
Cellular component	• integral to plasma membrane • membrane
Biological process	• cellular defense response

Orthologs

Species

Human

Mouse

n/a

n/a

n/a

n/a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)

n/a

n/a

PubMed search

n/a

T-cell receptor alpha chain C region is a protein that in humans is encoded by the TRA@ gene.^[1]^[2]^[3]

References

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Further reading

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This protein-related article is a stub. You can help Wikipedia by expanding it.

Transmembrane receptors: immunoglobulin superfamily immune receptors

Antibody receptor:
Fc receptor

Epsilon (ε)	FcεRI (FcεRII is C-type lectin)
Gamma (γ)	FcγRI FcγRII FcγRIII Neonatal
Alpha (α)/mu (μ)	FcαRI Fcα/μR
Secretory	Polymeric immunoglobulin receptor

Antigen receptor

Antigen receptor

BCR

stimulate:	CD21/CD19/CD81
inhibit:	CD22

Accessory molecules

Ig-α/Ig-β (CD79)

Ligands	MHC MHC class I MHC class II
Antigen receptor	TCR: TRA@ TRB@ TRD@ TRG@
Co-receptors	CD8 (with two glycoprotein chains CD8α and CD8β) CD4
Accessory molecules	CD3 CD3γ CD3δ CD3ε ζ-chain (also called CD3ζ and TCRζ)

Cytokine receptor

see cytokine receptors

Killer-cell IG-like receptors

Leukocyte IG-like receptors

v t e Index of signal transduction
Description	Intercellular neuropeptides growth factors cytokines hormones Cell surface receptors ligand-gated enzyme-linked G protein-coupled immunoglobulin superfamily integrins neuropeptide growth factor cytokine Intracellular adaptor proteins GTP-binding MAP kinase Calcium signaling Lipid signaling Pathways hedgehog Wnt TGF beta MAPK ERK notch JAK-STAT apoptosis hippo TLR

v t e Index of the immune system
Description	Physiology cells autoantigens autoantibodies complement surface antigens IG receptors
Disease	Allergies Immunodeficiency Immunoproliferative immunoglobulin disorders Hypersensitivity and autoimmune disorders Neoplasms and cancer
Treatment	Procedures Drugs antihistamines immunostimulants immunosuppressants monoclonal antibodies

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