Tropheryma whipplei
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T. whipplei
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| Tropheryma whipplei La Scola et al. 2001
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Tropheryma whipplei, formerly called Tropheryma whippelii,[1] is a bacterium and the causative organism of Whipple's disease[2] and rarely endocarditis
While T. whipplei is categorized with the Gram-positive Actinobacteria, the organism is commonly found to be Gram-negative or Gram-indeterminate when stained in the laboratory.[2] Whipple himself probably observed the organisms as rod-shaped structures with silver stain in his original case.[3]
History of the name
No name was given to the organism until 1991 when the name Tropheryma[4] whippelii was proposed after sections of the bacterial genome were sequenced.[5] The name was changed to Tropheryma whipplei in 2001 (correcting the spelling of Whipple's name) when the organism was deposited in bacterial collections.[2]
Pathogenesis
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Genome structure
Several strains of Tropheryma whipplei have been sequenced.[6][7]
References
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- ↑ From Greek τροφή trophê, "nourishment, food" and ἔρυμα eruma, "fence, a defence against, barrier".
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