U.S. Route 221 in South Carolina

This article is about the section of U.S. Route 221 in South Carolina. For the entire route, see U.S. Route 221.

U.S. Route 221
Route information
Maintained by SCDOT
Length:	126 mi (203 km)
Existed:	1932 – present
Major junctions
South end:	US 221 / SR 150 at the GA line near Pollards Corner, GA
	I-385 near Watts Mills I-26 near Moore I-585 / US 176 / SC 9 in Spartanburg I-85 near Spartanburg
North end:	US 221 at the SC line near Chesnee
Location
Counties:	McCormick, Greenwood, Laurens, Spartanburg, Cherokee
Highway system
United States Numbered Highways List Bannered Divided Replaced South Carolina Highways Interstate U.S. State Scenic ← SC 219 SC 223 →

U.S. Route 221 (US 221) is a part of the United States Numbered Highway System that runs from Perry in northern Florida to Lynchburg in central Virginia. In South Carolina, the highway runs north to south from the Georgia state line near Clarks Hill to the North Carolina state line near Chesnee. While in the state, the highway passes through Greenwood, Laurens, Woodruff, and Spartanburg. The highway mostly travels through rural parts of the Piedmont region of the state.

History

Established in 1932, US 221 was connected from North Carolina, from north of Cowpens National Battlefield to Greenwood, connecting the cities of Spartanburg, Woodruff, Laurens, and Waterloo. In 1941, US 221 replaced South Carolina Highway 110 (SC 110), going due north from Chesnee to the North Carolina state line; its former route became US 221 Alternate. In 1954, US 221 was extended south to Bradley and McCormick, then south over the Clarks Hill Dam into Georgia; this replaced part of SC 10 and part of SC 670.

Between 1962 and 1964, US 221 bypassed Roebuck. Between 1968 and 1970, US 221 was rerouted onto the Greenwood Bypass and its current routing south of US 25/US 178, replacing the remaining part of SC 670. The old route through Greenwood became SC 72 Business and an extension of SC 10.

Junction list

County	Location	mi	km	Destinations	Notes
Columbia	​			US 221 south / SR 150 south	Continuation into Georgia
Lake Strom Thurmond Savannah River		0.0	0.0	Georgia–South Carolina state line (J. Strom Thurmond Dam)
McCormick	Clarks Hill	1.8	2.9	SC 28	Southern end of SC 28 overlap
	Modoc	6.2	10.0	SC 23	Southern terminus of SC 23
	Plum Branch	15.6	25.1	SC 283	Northern terminus of SC 283
	McCormick	20.4	32.8	US 378 (Gold Street) / SC 28 (Mine Street)	Northern end of SC 28 overlap; southern end of US 378 overlap
		21.0	33.8	US 378 (Gold Street E)	Northern end of US 378 overlap
Greenwood	Bradley	29.5	47.5	SC 10 (McCormick Highway)	Southern end of SC 10 overlap
		31.8	51.2	SC 10 (McCormick Highway)	Northern end of SC 10 overlap
	Greenwood	40.2	64.7	SC 225
		41.1	66.1	US 25 / US 178 (Main Street S)	Southern end of US 25 / US 178 overlap
		42.5	68.4	SC 34 (Main Street W/Ninety Six Highway)
		45.9	73.9	US 25 / US 178 / SC 72 (Reynolds Avenue)	Northern end of US 25 / 178 overlap; southern end of SC 72 overlap
	Coronaca	50.8	81.8	SC 246
Laurens	Waterloo	54.2	87.2	SC 72	Northern end of SC 72 overlap
	Laurens	63.8	102.7	SC 39	Northern terminus of SC 39
		68.1	109.6	SC 127	Southern terminus of SC 127
		70.4	113.3	US 76 Bus. (Main Street E)
		70.9	114.1	US 76 (Hillcrest Drive/Fleming Street)
		72.4	116.5	SC 49 (Yarborough Mill Road)	Southern terminus of SC 49
		74.6	120.1	I-385	I-385 exit 9.
	Ora	76.8	123.6	SC 308	Western terminus of SC 308
	Enoree	80.7	129.9	SC 92	Southern end of SC 92 overlap
Spartanburg		82.2	132.3	SC 92 (Parker Road)	Northern end of SC 92 overlap
	Woodruff	89.3	143.7	SC 146 (Cross Anchor Road)	Southern end of SC 146 overlap
		89.8	144.5	SC 101 (Georgia Street)	Southern end of SC 101 overlap
		90.8	146.1	SC 101 / SC 146	Northern end of SC 146 / SC 101 overlap
	Moore	97.7	157.2	SC 290 (Moore Duncan Highway)	Eastern terminus of SC 290
	Roebuck	98.5	158.5	I-26	I-26 exit 28.
		101.0	162.5	SC 215 (Blackstock Road E/Stone Station Road)
		103.7	166.9	SC 295 (Southport Road)
	Spartanburg	106.8	171.9	SC 56 (Henry Street)	Southern end of SC 56 overlap
		107.2	172.5	US 29 (St John Street)
		107.4	172.8	SC 296 (Daniel Morgan Avenue E)
		108.1	174.0	SC 56 (Asheville Highway)	Northern end of SC 56 overlap
		108.9	175.3	I-585 / US 176 / SC 9 (Pine Street N)	I-585 exit 25B.
		113.0	181.9	I-85	I-85 exit 78.
	Chesnee	123.0	197.9	US 221 Alt. / SC 11 (Cherokee Street/Cherokee Foothills Scenic Highway)	Northern terminus of US 221 Alt
Cherokee		125.9	202.6	US 221 north	Continuation into North Carolina
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus

Bannered routes

Main article: Bannered routes of U.S. Route 221

There is one alternate route in South Carolina.

See also

• South Carolina portal
• U.S. Roads portal
• Bannered routes of U.S. Route 221
• Central Savannah River Area
• Enoree River
• Lake Greenwood
• Lake Strom Thurmond
• Saluda River
• Savannah River
• Sumter National Forest

External links

• Media related to at Wikimedia Commons

U.S. Route 221
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