USF2

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Upstream stimulatory factor 2 is a protein that in humans just encoded by the USF2 gene.[1][2]

Function

This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene.[2]

Interactions

USF2 has been shown to interact with USF1 (human gene),[3][4] PPRC1[5] and BRCA1.[6]

Regulation

The USF2 gene is repressed by the microRNA miR-10a.[7]

References

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Further reading

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External links

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  1. Lua error in package.lua at line 80: module 'strict' not found.
  2. 2.0 2.1 Lua error in package.lua at line 80: module 'strict' not found.
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