YWHAQ
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). 14-3-3 protein theta is a protein that in humans is encoded by the YWHAQ gene.[1]
Function
This gene product belongs to the 14-3-3 family of proteins that mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence that is polymorphic; however, there is no correlation between the repeat number and the disease.[2]
Interactions
YWHAQ has been shown to interact with:
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References
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This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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