Acireductone synthase

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Acireductone synthase
Identifiers
EC number 3.1.3.77
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Acireductone synthase (EC 3.1.3.77, E1, E-1 enolase-phosphatase) is an enzyme with systematic name 5-(methylthio)-2,3-dioxopentyl-phosphate phosphohydrolase (isomerizing).[1][2][3] This enzyme catalyses the following chemical reaction

5-(methylthio)-2,3-dioxopentyl phosphate + H2O \rightleftharpoons 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate (overall reaction)
(1a) 5-(methylthio)-2,3-dioxopentyl phosphate \rightleftharpoons 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate (probably spontaneous)
(1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O \rightleftharpoons 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate

References

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External links

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