BW373U86

From Infogalactic: the planetary knowledge core
Jump to: navigation, search
BW373U86
BW373U86.svg
Systematic (IUPAC) name
4-[(R)-[(2S,5R)-2,5-dimethyl-4-prop-2-enylpiperazin-1-yl]-(3-hydroxyphenyl)methyl]-N,N-diethylbenzamide
Identifiers
CAS Number 150428-54-9 YesY
PubChem CID: 10025998
ChemSpider 8201569 N
ChEMBL CHEMBL25230 N
Synonyms (+)BW373U86
Chemical data
Formula C27H37N3O2
Molecular mass 435.602 g/mol
  • O=C(N(CC)CC)c1ccc(cc1)[C@H](N2C[C@H](N(C\C=C)C[C@@H]2C)C)c3cccc(O)c3
  • InChI=1S/C27H37N3O2/c1-6-16-29-18-21(5)30(19-20(29)4)26(24-10-9-11-25(31)17-24)22-12-14-23(15-13-22)27(32)28(7-2)8-3/h6,9-15,17,20-21,26,31H,1,7-8,16,18-19H2,2-5H3/t20-,21+,26+/m1/s1 N
  • Key:LBLDMHBSVIVJPM-SWYRRKHMSA-N N
 NYesY (what is this?)  (verify)

(+)BW373U86 is an opioid analgesic drug used in scientific research.[1][2]

BW373U86 is a selective agonist for the δ-opioid receptor, with approximately 15x stronger affinity for the δ-opioid than the μ-opioid receptor.[3] It has potent analgesic and antidepressant effects in animal studies.[4][5] In studies on rats, BW373U86 appears to protect heart muscle cells from apoptosis in conditions of ischemia (oxygen deprivation, such as in heart attack). The mechanism for this is complex and may be separate from its delta agonist effects.[6][7][8]

References

<templatestyles src="Reflist/styles.css" />

Cite error: Invalid <references> tag; parameter "group" is allowed only.

Use <references />, or <references group="..." />


  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  5. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  6. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  7. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  8. ↑ Lua error in package.lua at line 80: module 'strict' not found.
Retrieved from "https://infogalactic.com/w/index.php?title=BW373U86&oldid=2872726"