Benzethidine

Benzethidine
	Ball-and-stick model of the benzethidine molecule
Systematic (IUPAC) name
	ethyl 1-[2-(benzyloxy)ethyl]- 4-phenylpiperidine- 4-carboxylate
Clinical data
Legal status	AU: S9 (Prohibited); CA: Schedule I; DE: Anlage I (Controlled); UK: Class A; US: Schedule I;
Identifiers
CAS Number	3691-78-9
ATC code	none
PubChem	CID: 62516
DrugBank	DB01518
ChemSpider	56290
UNII	X0I74BAR02
ChEMBL	CHEMBL2104234
Chemical data
Formula	C23H29NO3
Molecular mass	367.481 g/mol
	SMILES O=C(OCC)C3(c1ccccc1)CCN(CCOCc2ccccc2)CC3 ;
	InChI InChI=1S/C23H29NO3/c1-2-27-22(25)23(21-11-7-4-8-12-21)13-15-24(16-14-23)17-18-26-19-20-9-5-3-6-10-20/h3-12H,2,13-19H2,1H3 ; Key:UVTBZAWTRVBTMK-UHFFFAOYSA-N ;
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Benzethidine is a 4-phenyl piperidine derivative that is related to the opioid analgesic drug pethidine (meperidine, or Demerol).^[1]

Benzethidine is not currently used in medicine and is a Class A/Schedule I drug which is controlled under UN drug conventions. It has similar effects to other opioid derivatives, such as analgesia, sedation, nausea and respiratory depression.^[2]

References

↑ Maul C, Buschmann H, Sundermann B. Opioids: 3.3 Synthetic Opioids. Analgesics 2005; 159-169. ISBN 978-3-527-30403-5
↑ Cahal DA, Dare JG, Keith D. A Sequential Trial of Analgesics in Labour. International Journal of Obstetrics and Gynaecology 1961; 68(1): 88–93.

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