EIF2B2

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Translation initiation factor eIF-2B subunit beta is a protein that in humans is encoded by the EIF2B2 gene.[1][2]

Function

Eukaryotic initiation factor-2B (EIF2B) is a GTP exchange protein essential for protein synthesis. It consists of alpha (EIF2B1; MIM 606686), beta (EIF2B2), gamma (EIF2B3; MIM 606273), delta (EIF2B4; MIM 606687), and epsilon (EIF2B5; MIM 603945) subunits. EIF2B activates its EIF2 (see MIM 603907) substrate by exchanging EIF2-bound GDP for GTP.[2]

Interactions

EIF2B2 has been shown to interact with EIF2B5[3] and NCK1.[4]

References

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Further reading

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  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ 2.0 2.1 Lua error in package.lua at line 80: module 'strict' not found.
  3. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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