Inositol-polyphosphate 5-phosphatase

Inositol-polyphosphate 5-phosphatase
Identifiers
EC number	3.1.3.56
CAS number	Template:CAS
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Search PMC articles PubMed articles NCBI proteins

Inositol-polyphosphate 5-phosphatase (EC 3.1.3.56, type I inositol-polyphosphate phosphatase, inositol trisphosphate phosphomonoesterase, InsP3/Ins(1,3,4,5)P4 5-phosphatase, inosine triphosphatase, D-myo-inositol 1,4,5-triphosphate 5-phosphatase, D-myo-inositol 1,4,5-trisphosphate 5-phosphatase, L-myo-inositol 1,4,5-trisphosphate-monoesterase, inositol phosphate 5-phosphomonoesterase, inositol-1,4,5-trisphosphate/1,3,4,5-tetrakisphosphate 5-phosphatase, Ins(1,4,5)P3 5-phosphatase, D-myo-inositol(1,4,5)/(1,3,4,5)-polyphosphate 5-phosphatase, inositol 1,4,5-trisphosphate phosphatase, inositol polyphosphate-5-phosphatase, myo-inositol-1,4,5-trisphosphate 5-phosphatase, inositol-1,4,5-trisphosphate 5-phosphatase) is an enzyme with systematic name 1D-myo-inositol-1,4,5-trisphosphate 5-phosphohydrolase. This enzyme catalyses the following chemical reaction

(1) D-myo-inositol 1,4,5-trisphosphate + H₂O $\rightleftharpoons$ myo-inositol 1,4-bisphosphate + phosphate

(2) 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H₂O $\rightleftharpoons$ 1D-myo-inositol 1,3,4-trisphosphate + phosphate

One mammalian isoform is known.

External links

• Inositol-polyphosphate 5-phosphatase at the US National Library of Medicine Medical Subject Headings (MeSH)