MCM3AP

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Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). 80 kDa MCM3-associated protein is a protein that in humans is encoded by the MCM3AP gene.[1][2]

Function

The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is an MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization.[2]

Interactions

MCM3AP has been shown to interact with:

References

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Further reading

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