Methyldesorphine
Systematic (IUPAC) name | |
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(5α)-6,17-Dimethyl-6,7-didehydro-4,5-epoxymorphinan-3-ol
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Clinical data | |
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Identifiers | |
CAS Number | 16008-36-9 |
ATC code | none |
PubChem | CID: 5362518 |
ChemSpider | 4515065 |
UNII | Y460N7W76B |
Synonyms | 3-Hydroxy-6,N-dimethyl- 4,5-epoxymorphin-6-en |
Chemical data | |
Formula | C18H21NO2 |
Molecular mass | 283.36 g/mol |
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Methyldesorphine is an opioid analgesic. First synthesized in Germany in 1940 and patented in the USA in 1952,[1] it has a high potential for abuse as with any potent opioid agonist, and is sometimes found along with desomorphine as a component of the home-made opioid mixture known as "Krokodil" used in Russia and the neighboring former Soviet republics.[2] It is approximately 15 times more potent than morphine as an analgesic[3][4] but if the 6-7 bond is saturated, the β isomer is some 50 times more potent than morphine.
Methyldesorphine is listed as a Schedule I Narcotic controlled substance under the Controlled Substances Act 1970 in the United States with a DEA ACSCN of 9302 and zero annual aggregate manufacturing quota. The free base conversion ratio of the hydrochloride is 0.89.[5]
See also
References
- ↑ US patent 2694068, Payne, G. B. et al., "Δ6-DESOXYMORPHINE COMPOUNDS AND PROCESS OF PRODUCING THE SAME", published 1952-08-05, issued 1954-09-11
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- ↑ http://www.deadiversion.usdoj.gov/quotas/conv_factor/index.html
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