Sodium–hydrogen antiporter 3
Lua error in Module:Infobox_gene at line 33: attempt to index field 'wikibase' (a nil value). Sodium–hydrogen antiporter 3 also known as sodium–hydrogen exchanger 3 (NHE3) or solute carrier family 9 member 3 (SLC9A3) is a protein that in humans is encoded by the SLC9A3 gene.[1][2]
SLC9A3 is a sodium–hydrogen antiporter. It is found in the tubulus proximal of the nephron of the kidney and in the apical membrane of enterocytes of the intestine. It is primarily responsible for maintaining the balance of sodium.[3]
Contents
Regulation
Protein kinase C stimulates NHE3, while protein kinase A inhibits it.[4]
There is a specific protein functioning as an NHE3 regulator, Sodium-hydrogen antiporter 3 regulator 1.
Inhibitors
Stimulators
Interactions
Sodium–hydrogen antiporter 3 has been shown to interact with CHP.[7]
References
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External links
- Sodium-Hydrogen Exchanger at the US National Library of Medicine Medical Subject Headings (MeSH)
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- ↑ Lua error in package.lua at line 80: module 'strict' not found.
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- ↑ VI. Mechanisms of Salt & Water Reabsorption
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