Thymidylate 5'-phosphatase

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thymidylate 5'-phosphatase
Identifiers
EC number 3.1.3.35
CAS number Template:CAS
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a thymidylate 5'-phosphatase (EC 3.1.3.35) is an enzyme that catalyzes the chemical reaction

thymidylate + H2O \rightleftharpoons thymidine + phosphate

Thus, the two substrates of this enzyme are thymidylate and H2O, whereas its two products are thymidine and phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name of this enzyme class is thymidylate 5'-phosphohydrolase. Other names in common use include thymidylate 5'-nucleotidase, deoxythymidylate 5'-nucleotidase, thymidylate nucleotidase, deoxythymidylic 5'-nucleotidase, deoxythymidylate phosphohydrolase, and dTMPase.

References

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