ZM-241,385
From Infogalactic: the planetary knowledge core
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Names | |
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IUPAC name
4-(2-(7-amino-2-(furan-2-yl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-ylamino)ethyl)phenol
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Identifiers | |
139180-30-6 ![]() |
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ChEMBL | ChEMBL1628689 ![]() |
ChemSpider | 153646 ![]() |
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Jmol 3D model | Interactive image |
PubChem | 176407 |
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Properties | |
C16H15N7O2 | |
Molar mass | 337.34 g·mol−1 |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references | |
ZM-241,385 is a high affinity antagonist ligand selective for the adenosine A2A receptor.[1]
In animal models, ZM-241,385 has been shown to protect against beta amyloid neurotoxicity and therefore may be useful as a treatment for Alzheimer's disease.[2] ZM-241,385 has also been shown to enhance L-DOPA derived dopamine release and therefore may be useful in the treatment of Parkinson's disease.[3]
References
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External links
ZM 241385 at the US National Library of Medicine Medical Subject Headings (MeSH)
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