17-Phenylandrostenol

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17-Phenylandrostenol
17-Phenylandrostenol.png
Systematic (IUPAC) name
(3R,5S,8R,9S,10S,13S,14S)-10,13-dimethyl-17-phenyl- 2,3,4,5,6,7,8,9,11,12,14,15-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
Identifiers
CAS Number 694438-95-4 N
PubChem CID: 25068278
ChemSpider 21475142 YesY
Synonyms (3α,5α)-17-Phenyl-androst-16-en-3-ol
Chemical data
Formula C25H34O
Molecular mass 350.535 g/mol
  • C[C@]12CC[C@H](C[C@@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC=C4C5=CC=CC=C5)C)O
  • InChI=1S/C25H34O/c1-24-14-12-19(26)16-18(24)8-9-20-22-11-10-21(17-6-4-3-5-7-17)25(22,2)15-13-23(20)24/h3-7,10,18-20,22-23,26H,8-9,11-16H2,1-2H3/t18-,19+,20-,22-,23-,24-,25+/m0/s1 YesY
  • Key:SINAMTXBCYKFDL-WBJZGETLSA-N YesY
 NYesY (what is this?)  (verify)

17-Phenylandrostenol (17-PA), or (3α,5α)-17-phenylandrost-16-en-3-ol, is a steroid drug which binds to GABAA receptors. It acts as an antagonist against the sedative effects of neuroactive steroids, but has little effect when administered by itself, and does not block the effects of benzodiazepines or barbiturates.[1][2]

See also

References

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