Encainide

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Encainide
File:EncainideRedrawn.svg
Systematic (IUPAC) name
4-methoxy-N-[2-(1-methyl-2-piperidin-1-ylethyl)phenyl]benzamide
Clinical data
Trade names Enkaid
AHFS/Drugs.com Micromedex Detailed Consumer Information
MedlinePlus a605040
Legal status
  • Withdrawn
Identifiers
CAS Number 66778-36-7 YesY
ATC code C01BC08 (WHO)
PubChem CID: 48041
DrugBank DB01228 YesY
ChemSpider 43697 YesY
UNII SY3J0147NB YesY
KEGG D07894 YesY
ChEBI CHEBI:4788 YesY
ChEMBL CHEMBL315838 N
Chemical data
Formula C22H28N2O2
Molecular mass 352.47 g/mol
  • CN1CCCCC1CCC2=CC=CC=C2NC(=O)C3=CC=C(C=C3)OC
  • InChI=1S/C22H28N2O2/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25) YesY
  • Key:PJWPNDMDCLXCOM-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

Encainide (trade name Enkaid) is a class Ic antiarrhythmic agent. It is no longer used because of its frequent proarrhythmic side effects.[1]

Synthesis

File:Encainide synthesis.png
Encainide synthesis:[2][3][4]

Lidamidine

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See also

References

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  1. ↑ Lua error in package.lua at line 80: module 'strict' not found.
  2. ↑ S.J. Dykstra, J.L. Minelli, DE 2210154  (1972).
  3. ↑ S.J. Dykstra, J.L. Minelli, U.S. Patent 3,931,195 (1976).
  4. ↑ Lua error in package.lua at line 80: module 'strict' not found.
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