Dipraglurant

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Dipraglurant
Dipraglurant.svg
Systematic (IUPAC) name
6-Fluoro-2-[4-(2-pyridinyl)-3-butyn-1-yl]imidazo[1,2-a]pyridine
Identifiers
CAS Number 872363-17-2
ATC code None
PubChem CID: 44557636
ChemSpider 25069676
Chemical data
Formula C16H12FN3
Molecular mass 265.285 g/mol
  • c1ccnc(c1)C#CCCc2cn3cc(ccc3n2)F
  • InChI=1S/C16H12FN3/c17-13-8-9-16-19-15(12-20(16)11-13)7-2-1-5-14-6-3-4-10-18-14/h3-4,6,8-12H,2,7H2
  • Key:LZXMUJCJAWVHPZ-UHFFFAOYSA-N

Dipraglurant (INN) (code name ADX-48621) is a negative allosteric modulator of the mGlu5 receptor which is under development by Addex Therapeutics for the treatment of Parkinson's disease levodopa-induced dyskinesia (PD-LID).[1][2][3] As of 2014, it is in phase II clinical trials for this indication.[1] Addex Therapeutics is also investigating an extended-release formulation of dipraglurant for the treatment of non-parkinsonian dystonia.[4]

See also

References

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External links



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