VUF-5681
From Infogalactic: the planetary knowledge core
Names | |
---|---|
IUPAC name
4-[3-(1H-Imidazol-4-yl)propyl]piperidine
|
|
Identifiers | |
768358-61-8 | |
ChemSpider | 8505701 |
Jmol 3D model | Interactive image |
PubChem | 10330240 |
|
|
|
|
Properties | |
C11H19N3 | |
Molar mass | 193.288 |
Vapor pressure | {{{value}}} |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
|
verify (what is ?) | |
Infobox references | |
VUF-5681 is a potent and selective histamine antagonist which binds selectively to the H3 subtype.[1] However while VUF-5681 blocks the activity of more potent H3 agonists, recent studies suggest that it may have some weak partial agonist activity when administered by itself.[2]
References
- ↑ Moreno-Delgado D, Torrent A, Gómez-Ramírez J, de Esch I, Blanco I, Ortiz J. Constitutive activity of H3 autoreceptors modulates histamine synthesis in rat brain through the cAMP/PKA pathway. Neuropharmacology. 2006 Sep;51(3):517-23. PMID 16769092
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
<templatestyles src="Asbox/styles.css"></templatestyles>
Categories:
- Articles without EBI source
- Articles without KEGG source
- Articles without UNII source
- Articles with changed InChI identifier
- Pages using collapsible list with both background and text-align in titlestyle
- Chemical articles using a fixed chemical formula
- H3 receptor antagonists
- Imidazoles
- Piperidines
- Pharmacology stubs