Rev-ErbA
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The Rev-ErbA proteins are members of the nuclear receptor family of intracellular transcription factors. There are two forms of the receptor, alpha and beta, each encoded by a separate gene (NR1D1 and NR1D2 respectively).[1][2]
The rev-Erb-α gene is highly unusual in that it is encoded on the opposite strand of the alpha-thyroid hormone receptor (TR) gene.[1]
The rev-Erb-α protein is a key regulatory component of the circadian clock.[3][4] In addition, rev-Erb-α appears also to regulate the breakdown of cartilage.[5]
References
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<references />, or <references group="..." />External links
- HZF-2alpha at the US National Library of Medicine Medical Subject Headings (MeSH)
- HZF-2beta at the US National Library of Medicine Medical Subject Headings (MeSH)
- NR1D1 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)
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