TRPC3

Transient receptor potential cation channel, subfamily C, member 3
Transient receptor potential cation channel, subfamily C, member 3
Identifiers
Symbols	TRPC3 ; SCA41; TRP3
External IDs	OMIM: 602345 MGI: 109526 HomoloGene: 20708 IUPHAR: 488 GeneCards: TRPC3 Gene
Gene ontology
Molecular function	• calcium channel activity; • protein binding; • store-operated calcium channel activity; • inositol 1,4,5 trisphosphate binding;
Cellular component	• cytosol; • plasma membrane; • integral component of plasma membrane;
Biological process	• calcium ion transport; • manganese ion transport; • axon guidance; • blood coagulation; • phototransduction; • positive regulation of calcium ion transport into cytosol; • platelet activation; • response to ATP; • ion transmembrane transport; • cytosolic calcium ion homeostasis; • response to calcium ion; • transmembrane transport; • calcium ion transmembrane transport; • positive regulation of cardiac muscle hypertrophy in response to stress;
	Sources: Amigo / QuickGO
RNA expression pattern
	File:PBB GE TRPC3 206425 s at tn.png
	File:PBB GE TRPC3 210814 at tn.png
	More reference expression data
Orthologs
Species	Human
Entrez	7222
Ensembl	ENSG00000138741
UniProt	Q13507
RefSeq (mRNA)	NM_001130698
RefSeq (protein)	NP_001124170
Location (UCSC)	Chr 4:; 121.88 – 121.95 Mb
PubMed search	[1]
	v; t; e;

Transient receptor potential cation channel, subfamily C, member 3, also known as TRPC3, is a human gene encoding a protein of the same name.

Interactions

TRPC3 has been shown to interact with TRPC1^[1]^[2] and TRPC6.^[3]

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TRPC3 protein, human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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