7-OH-DPAT

7-OH-DPAT
Names
	IUPAC name 7-Hydroxy-N,N-dipropyl-2-aminotetralin[citation needed]
	Systematic IUPAC name 7-(Dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol
Identifiers
CAS Number	74938-11-7
Abbreviations	7-OH-DPAT
ChEMBL	ChEMBL285755
ChemSpider	1182 ; 5036175 (R)
IUPHAR/BPS	950
Jmol 3D model	Interactive image; Interactive image
MeSH	7-Hydroxy-2-N,N-dipropylaminotetralin
PubChem	1219; 6603867 (R); 23928184 (S)
	InChI InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 Key: BLYMJBIZMIGWFK-UHFFFAOYSA-N ; InChI=1/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3 Key: BLYMJBIZMIGWFK-UHFFFAOYAH ;
	SMILES CCCN(CCC)C1CCc2ccc(O)cc2C1 ; CCCN(CCC)C1CCC2=C(C1)C=C(O)C=C2 ;
Properties
Chemical formula	C16H25NO
Molar mass	247.38 g·mol−1
log P	3.653
Acidity (pKa)	10.389
Basicity (pKb)	3.608
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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	Infobox references

7-OH-DPAT is a synthetic compound that acts as a dopamine receptor agonist with reasonable selectivity for the D₃ receptor subtype,^[2]^[3]^[4] and low affinity for serotonin receptors, unlike its structural isomer 8-OH-DPAT.^[5]^[6]^[7] 7-OH-DPAT is self-administered in several animal models, and is used to study addiction to cocaine.^[8]^[9]^[10]^[11]^[12]

References

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