2β-Propanoyl-3β-(4-tolyl)-tropane

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2β-Propanoyl-3β-(4-tolyl)-tropane
WF-11.svg
Systematic (IUPAC) name
2β-Propanoyl-3β-(4-tolyl)-tropane
Identifiers
CAS Number 152783-29-4
Chemical data
Formula C18H25NO
Molecular mass 271.396 g/mol

2β-Propanoyl-3β-(4-tolyl)-tropane also known as WF-11 or PTT is a cocaine analogue 20 times more potent than cocaine at binding to the dopamine transporter with increased selectivity for the norepinephrine transporters. It also shows marked increase in metabolic stability. In contrast to the findings of cocaine effects, WF-11 has been shown to produce a uniform downregulation of tyrosine hydroxylase protein and activity gene expression with a regimen of use.[1]

See also

References

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