Rauwolscine

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Rauwolscine
Rauwolscine.png
Systematic (IUPAC) name
17α-hydroxy-20α-yohimban-16β-carboxylic acid methyl ester
Clinical data
Legal status
  • Uncontrolled
Routes of
administration		 Oral
Identifiers
CAS Number 131-03-3 N 6211-32-1 (HCl)
ATC code none
PubChem CID: 643606
IUPHAR/BPS 136
ChemSpider 558737 YesY
ChEBI CHEBI:48562 YesY
ChEMBL CHEMBL10347 YesY
Chemical data
Formula C21H26N2O3
Molecular mass 354.44 g/mol
  • InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15+,17+,18+,19+/m1/s1 YesY
  • Key:BLGXFZZNTVWLAY-DIRVCLHFSA-N YesY
 NYesY (what is this?)  (verify)

Rauwolscine, also known as isoyohimbine, α-yohimbine, and corynanthidine, is an alkaloid found in various species within the genera Rauwolfia and Pausinystalia (formerly known as Corynanthe).[1] It is a stereoisomer of yohimbine.[1] Rauwolscine is a central nervous system stimulant, a local anesthetic and a vague aphrodisiac.[1]

Rauwolscine acts predominantly as a α2-adrenergic receptor antagonist.[2] [3]It has also been shown to function as a 5-HT1A receptor partial agonist and 5-HT2A and 5-HT2B receptor antagonist.[4][5][6]

See also

References

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