Fenspiride

Fenspiride

Systematic (IUPAC) name
8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
Clinical data
Trade names	Eurespal, Pneumorel
AHFS/Drugs.com	International Drug Names
Legal status	℞ (Prescription only)
Routes of administration	Oral
Pharmacokinetic data
Bioavailability	90%
Biological half-life	14–16 hours
Excretion	Urine (90%), feces (~10%)
Identifiers
CAS Number	5053-06-5 Y
ATC code	R03BX01 (WHO) R03DX03
PubChem	CID: 68626
DrugBank	DB08979 N
ChemSpider	3227
UNII	S983QC7HKM N
KEGG	D07949 Y
ChEMBL	CHEMBL576127 N
Chemical data
Formula	C15H20N2O2
Molecular mass	260.331 g/mol
SMILES c1ccc(cc1)CCN2CCC3(CC2)CN=C(O3)O
InChI InChI=1S/C15H20N2O2/c18-14-16-12-15(19-14)7-10-17(11-8-15)9-6-13-4-2-1-3-5-13/h1-5H,6-12H2,(H,16,18) Key:FVNFBBAOMBJTST-UHFFFAOYSA-N
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Fenspiride (INN, brand names Eurespal, Pneumorel and others) is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. The pharmacotherapeutic classification is antitussives. In Russia it is approved for the treatment of acute and chronic inflammatory diseases of ENT organs (ear, nose, throat) and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis), as well as for maintenance treatment of asthma.