2-Aminotetralin

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2-Aminotetralin
2-Aminotetralin.png
Systematic (IUPAC) name
1,2,3,4-tetrahydronaphthalen-2-amine
Clinical data
Legal status
  • Uncontrolled
Routes of
administration		 Oral
Identifiers
CAS Number 2954-50-9 N
ATC code none
PubChem CID: 34677
ChemSpider 31912 YesY
ChEMBL CHEMBL30294 YesY
Chemical data
Formula C10H13N
Molecular mass 147.217 g/mol
  • C1CC2=CC=CC=C2CC1N
  • InChI=1S/C10H13N/c11-10-6-5-8-3-1-2-4-9(8)7-10/h1-4,10H,5-7,11H2 YesY
  • Key:LCGFVWKNXLRFIF-UHFFFAOYSA-N YesY
 NYesY (what is this?)  (verify)

2-Aminotetralin (2-AT), also known as 1,2,3,4-tetrahydronaphthalen-2-amine (THN), is a stimulant drug with a chemical structure consisting of a tetralin group combined with an amine.[1][2]

2-AT is a rigid analogue of phenylisobutylamine and fully substitutes for d-amphetamine in rat discrimination tests, although at one eighth the potency.[1] It has been shown to inhibit the reuptake of serotonin and norepinephrine, and likely induces their release as well.[3][4] It is also likely to act on dopamine on account of its full substitution of d-amphetamine in rodent studies.[1]

Chemical derivatives

A number of derivatives of 2-aminotetralin exist, including:

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See also

References

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