2β-Propanoyl-3β-(2-naphthyl)-tropane
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Systematic (IUPAC) name | |
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2β-Propanoyl-3β-(2-naphthyl)-tropane
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Pharmacokinetic data | |
Bioavailability | high |
Metabolism | slow |
Chemical data | |
Formula | C21H25NO |
Molecular mass | 307.43 g/mol |
2β-Propanoyl-3β-(2-naphthyl)-tropane or WF-23 is a cocaine analogue. It is claimed to be several hundred times more potent than cocaine at being serotonin-norepinephrine-dopamine reuptake inhibitor.[1]
As can be seen on pubmed, these acyl substituted phenyltropanes are highly potent MAT inhibitors and also have a very long half-life, spanning perhaps at least a few days.[2][3]
See also
External links
- (Satendra Singh, 2000) Page 16-17
References
- ↑ U.S. Patent 6,008,227
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
- ↑ Lua error in package.lua at line 80: module 'strict' not found.
2-Carboxymethyl Esters | |
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(3,4-Disubstituted Phenyl)-tropanes | |
Arylcarboxy | |
Carboxyalkyl | |
Acyl | |
β,α Stereochemistry | |
α,β Stereochemistry | |
Heterocycles: 3-Substituted-isoxazol-5-yl | |
Heterocycles: 3-Substituted-1,2,4-oxadiazole | |
N-alkyl | |
N-replaced (S,O,C) | |
Irreversible | |
Nortropanes (N-demethylated) |
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